Methyl 3-[3-(Aryl)-1,2,4-Oxadiazol-5-Yl]Propionates
نویسندگان
چکیده
منابع مشابه
PYRAZOLINES AND ISOXAZOLINES (I). SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF P-(1-ACYL-3-METHYL-5-ARYL-4 PYRAZOLINOYL / P-(3-METHYL-5-ARYL-4ISOXAZOLINOYL) ARSANILIC ACID
4-(acetoacetamido) arsanilic acid (II), which was then condensed with aryl aldehydes. The resulting product on reaction with hydrazine hydrate and hydroxyl amine hydrochloride yielded Pyrazolines (IV) and Isoxazolines (V), respectively. The antimicrobial activity of compounds against a number of microorganisms was evaluated. Some of these compounds showed significant antimicrobial activity
متن کامل3-[3-(3-Fluorophenyl)-1,2,4-oxadiazol-5-yl]propionic acid
In the title compound, C(11)H(9)FN(2)O(3), the benzene ring is almost coplanar with the heterocyclic ring, making a dihedral angle of 14.0 (1)°. The plane of the carboxyl group is rotated by 14.7 (3)° with respect to the 1,2,4-oxadiazole ring plane. The aliphatic chain exhibits a standard zigzag arrangement. Two inter-molecular O-H⋯O hydrogen bonds between the carboxyl groups related by an inve...
متن کاملpyrazolines and isoxazolines (i). synthesis and antimicrobial activities of p-(1-acyl-3-methyl-5-aryl-4 pyrazolinoyl / p-(3-methyl-5-aryl-4isoxazolinoyl) arsanilic acid
4-(acetoacetamido) arsanilic acid (ii), which was then condensed with aryl aldehydes. the resulting product on reaction with hydrazine hydrate and hydroxyl amine hydrochloride yielded pyrazolines (iv) and isoxazolines (v), respectively. the antimicrobial activity of compounds against a number of microorganisms was evaluated. some of these compounds showed significant antimicrobial activity
متن کامل4-[4-(4-Amino-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine
The complete molecule of the compound, C(6)H(4)N(8)O(3), is generated by a crystallographic twofold rotation axis that runs through the central ring. The flanking ring is twisted by 20.2 (1)° with respect to the central ring. One of the amino H atoms forms an intra-molecular N-H⋯N hydrogen bond; adjacent mol-ecules are linked by N-H⋯N hydrogen bonds forming a chain running along [10-2].
متن کاملA handy and solventless direct route to primary 3-[3-aryl)-1,2,4-oxadiazol-5-yl]propionamides using microwave irradiation.
A one-step, simple and straightforward synthesis of the title amides from the corresponding carboxylic acids, urea and imidazole under microwave irradiation is described.
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ژورنال
عنوان ژورنال: Journal Of The Brazilian Chemical Society
سال: 1992
ISSN: 0103-5053
DOI: 10.5935/0103-5053.19920025